By Dr. Killeen, published on January 19, 2026
The current evidence does not support delaying a breast reduction if you are on Accutane. And that is my personal practice.
For many years, the standard recommendation was to stop Accutane (isotretinoin) at least six months before surgery. The concern was that the medication would cause significant wound healing problems. Patients were told to either finish their entire course first or pause it well in advance.
We now have good evidence that Accutane does not impede wound healing. The old six-month rule is no longer supported by the data.
This means it is completely reasonable to proceed with breast reduction surgery while on Accutane. There is no need to delay.
In my practice, I typically do not delay surgery for patients on Accutane. The current evidence supports this approach.
That said, you will find surgeons who still prefer to wait — and that's their prerogative. If your surgeon recommends delaying, it's worth having a conversation about the reasoning and the latest research.